Today's Concept of the Tuberculin Test.
نویسندگان
چکیده
T HE TUBERCULIN TEST IS THE MOST effective means for detecting tuberculous infection, and hence is an essential tool in ultimate eradication of the disease. In clinical practice it has been generally accepted that a positive tuberculin skin reaction indicates the possibility of tuberculosis, whereas a negative reaction, with few exceptions, rules out a tuberculous infection. Since the advent of isoniazid chemoprophylaxis, the tuberculin test has become essential for tuberculosis prevention by reason of its usefulness in revealing tuberculosis in the incipient stage, at which time administration of isoniazid may prevent the development of overt disease. Until recently, all positive tuberculin skin reactions have been attributed to infection by Mycobacterium tuberculosis. This view has been challenged lately with the increasing knowledge of other mycobacterial infections causing tuberculin cross sensitivity in man. This tuberculin cross reaction has posed a new problem in the interpretation of the tuberculin test. The purpose of this article is to bring up to date the interpretation of the tuberculin skin reaction in the light of present-day knowledge of tuberculosis and other mycobacterial infections based on studies in the Houston area, as well as on published works in current literature. The tuberculin patch test and the recently introduced Heaf and tine tests will be discussed in terms of their reliability and feasibility.
منابع مشابه
A Comparison of Two-Step Tuberculin Skin Test between Health-Care Workers and Nonhospital Employees
Background: The tuberculin test is widely used to identify tuberculosis infection. Some individuals infected with Mycobacterium tuberculosis may have an initial negative skin test reaction to tuberculin. The two step purified protein derivative skin test can decrease misinterpretation of tuberculin test .This study was aimed at comparing the two- step tuberculin skin test and booster phenomenon...
متن کاملFrequency of Latent Tuberculosis Infection in Patients with Type 2 Diabetes referred to Shahid Rahimi Hospital in Khorramabad City with Tuberculin Skin Test in 2018-2020
Introduction: Tuberculosis is the leading cause of death from infectious diseases worldwide. Diabetes has been suggested as an important risk factor for tuberculosis. To date, few studies have examined the association between diabetes and tuberculosis. In this study, the prevalence of latent tuberculosis in diabetic patients was investigated. Methods: In this study, 195 patients with type 2 d...
متن کاملThe Booster Phenomenon of Tuberculin Skin Testing in Patients Receiving Hemo-dialysis
Background: The risk of developing tuberculosis is high among chronic hemodialysis patients. The tuberculin skin test (TST) has been in use for diagnosing latent TB, but few data are available on TST in hemodialysis patients. Objective: This study was done to identify the TST reactivity and frequency of booster effect in serial TST among hemodialysis patients. Methods: A total of 100 patients i...
متن کاملA suevey on the tuberculin test results of hospital staff in Hamedan medical sciences university
Controversies have been reported in recent studies regarding the risk of T.B contamination for hospital personnel.some of the experts consider all of the hospital staff in high risk groupd whill others consider the risk only for hospital staff working in the wards in which T.B patients are hospitalized.therefore in this study tuberculin test results of hospital clinical staff was compared to t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Diseases of the chest
دوره 46 شماره
صفحات -
تاریخ انتشار 1964